主要学术成果：

论文：

1

C. Gao^#, J. Jiang^#, P. Ma, P. Cheng, Y. Lian, B. Zhao, C. Li, Y. Peng, F. Wang, Y. Lin, N. Jin, J. Li, L. Wang, Q. Li, Y. Leng, J. Xia^*, and Z. Qi^*, “Arsenic Trioxide Induces T Cell Apoptosis and Prolongs Islet Allograft Survival in Mice,” Transplantation, vol. 99, pp. 1796–806, Sep. 2015.

2

P. P. Cheng^#, X. C. Liu^#, P. F. Ma, C. Gao, J. L. Li, Y. Y. Lin, W. Shao, S. Han, B. Zhao, L. M. Wang, J. Z. Fu, L. X. Meng, Q. Li, Q. Z. Lian^*, J. J. Xia^*, and Z. Q. Qi^*, “iPSC-MSCs Combined with Low-Dose Rapamycin Induced Islet Allograft Tolerance Through Suppressing Th1 and Enhancing Regulatory T-Cell Differentiation,” Stem Cells Dev, vol. 24, pp. 1793–804, Aug. 2015.

3

C. Li^#, T. Guan^#, C. Gao, Y. Lin, G. Yan, M. Zhu, C. Lv, J. Xia^*, and Z. Qi^*, “Arsenic trioxide inhibits accelerated allograft rejection mediated by alloreactive CD8 memory T cells and prolongs allograft survival time,” Transpl Immunol, Jun. 2015.

4

W. Chen^#, Y. Wu^#, A. Shimizu, Y. Lian, M. Tasaki, V. Villani, S. Moran, J. Xia, K. Yamada, and Z. Qi^*, “Rat-to-Chinese tree shrew heart transplantation is a novel small animal model to study non-Gal-mediated discordant xenograft humoral rejection,” Xenotransplantation, Nov. 2015.

5

Ma PF^#, Jiang J^#, Gao C, Cheng PP, Li JL, Huang X, Lin YY, Li Q, Peng YZ, Cai MC, Shao W, Zhu Q, Han S, Qin Q, Xia JJ^*, Qi ZQ^*. Immunosuppressive effect of compound K on islet transplantation in an STZ-induced diabetic mouse model. Diabetes. 2014;63(10):3458-69.

6

Cheng PP^#, Xia JJ, Wang HL, Chen JB, Wang FY, Zhang Y, Huang X, Zhang QJ, Qi ZQ^*. Islet transplantation reverses the effects of maternal diabetes on mouse oocytes. Reproduction. 2011;141(4):417-24.

7

Xia J^#, Chen J, Shao W, Lan T, Wang Y, Xie B, Thorlacius H, Tian F, Huang R^*, Qi Z^*. Suppressing memory T cell activation induces islet allograft tolerance in alloantigen-primed mice. Transpl Int. 2010;23(11):1154-63.

8

Su Z^#, Xia J^#, Shao W, Cui Y, Tai S, Ekberg H, Corbascio M, Chen J^*, Qi Z^*. Small islets are essential for successful intraportal transplantation in a diabetes mouse model. Scand J Immunol. 2010;72(6):504-10.

9

F. Wang^#, J. Xia^#, J. Chen^#, Y. Peng, P. Cheng, H. Ekberg, X. Wang, and Z. Qi^*, “Combination of antibodies inhibits accelerated rejection mediated by memory T cells in xenoantigen-primed mice,” Xenotransplantation, vol. 17, pp. 460–8, Dec. 2010

10

Chen J^#, Xia J, Axelsson B, Fritzson I, Ekberg H, Torngren M, Qi Z^*. An N-(alkylcarbonyl)anthranilic acid derivative prolongs cardiac allograft survival synergistically with cyclosporine A in a high-responder rat model. Transpl Immunol. 2010;23(4):180-4.

主持课题：

1

福建省自然科学基金面上项目，新型异种心脏移植模型建立及机制研究，2016.04-2019.03。

2

国家自然科学基金青年项目，MAPK信号通路在三氧化二砷抑制T细胞介导同种异体器官移植免疫排斥中的作用机制，2014.01-2016.12。

3

厦门大学基础创新科研基金，MSC与iPS辅助胰岛移植的应用及其机制研究，2011.07-2013.06。